Barakacin: A Thiazolyl-indole Alkaloid Isolated from Ruminal Pseudomonas sp
نویسندگان
چکیده
Barakacin: A Thiazolyl-indole Alkaloid Isolated from Ruminal Pseudomonas sp. Imene Zendah , Khaled A. Shaaban , Elisabeth Helmke , Armin Maier , Heinz H. Fiebig , and Hartmut Laatsch a, a Institute of Organic and Biomolecular Chemistry, Georg-August University, Tammannstrasse 2, D-37077 Göttingen, Germany b Alfred-Wegener-Institute for Polar and Marine Research, Am Handelshafen 12, D-27570 Bremerhaven, Germany c Oncotest GmbH, Am Flughafen 12-14, D-79108 Freiburg, Germany
منابع مشابه
Naucleamides A-E, new monoterpene indole alkaloids from Nauclea latifolia.
Five new monoterpene indole alkaloids, naucleamides A-E (1-5), were isolated from the bark and wood of Nauclea latifolia, and the structures and relative stereochemistry were elucidated from the spectroscopic data. Naucleamide E (5) is a unique monoterpene indole alkaloid possessing a pentacyclic ring system with an amino acetal bridge.
متن کاملIsolation, Characterization, and Bioactivity Evaluation of 3-((6-Methylpyrazin-2-yl)methyl)-1H-indole, a New Alkaloid from a Deep-Sea-Derived Actinomycete Serinicoccus profundi sp. nov
One new alkaloid, 3-((6-methylpyrazin-2-yl)methyl)-1H-indole (1) was obtained from the deep-sea actinomycete Serinicoccus profundi sp. nov., along with five known compounds (2-6). Their structures were determined on the basis of detailed analysis of the 1D and 2D NMR as well as MS data. The new indole alkaloid displayed weak antimicrobial activity against Staphylococcus aureus ATCC 25923 with a...
متن کاملFungal endophytes of Catharanthus roseus enhance vindoline content by modulating structural and regulatory genes related to terpenoid indole alkaloid biosynthesis
Not much is known about the mechanism of endophyte-mediated induction of secondary metabolite production in Catharanthus roseus. In the present study two fungal endophytes, Curvularia sp. CATDLF5 and Choanephora infundibulifera CATDLF6 were isolated from the leaves of the plant that were found to enhance vindoline content by 229-403%. The isolated endophytes did not affect the primary metabolis...
متن کاملA New Erythrinan Alkaloid Glycoside from the Seeds of Erythrina crista-galli.
A new Erythrina alkaloid glycoside, named erythraline-11β-O-glucopyranoside, was isolated from the seeds of Erythrina crista-galli L., together with five known Erythrina alkaloids and an indole alkaloid. The structure of the new alkaloid glycoside was elucidated by spectroscopic methods, and all of the compounds were evaluated for their antiviral activity against tobacco mosaic virus.
متن کاملErgot alkaloid transport across ruminant gastric tissues.
Ergot alkaloids cause fescue toxicosis when livestock graze endophyte-infected tall fescue. It is generally accepted that ergovaline is the toxic component of endophyte-infected tall fescue, but there is no direct evidence to support this hypothesis. The objective of this study was to examine relative and potential transport of ergoline and ergopeptine alkaloids across isolated gastric tissues ...
متن کامل